People who do not have celiac disease and believe they have "non-celiac gluten sensitivity" may be weaning themselves off gluten unnecessarily, researchers from the University of Pavia, Pavia, Italy, reported in Annals of Internal Medicine. The authors added that the majority of people who avoid gluten have "nonceliac gluten sensitivity" - those with celiac disease are a minority among gluten avoiders. Individuals with celiac disease have a condition in which the lining of the small intestine becomes damaged; undermining their ability to absorb nutrients from food properly... (Source: Health News from Medical News Today)MedWorm Sponsor Message: Please support the Doctors In Chains campaign for the medics tortured and sentenced for up to 15 years in Bahrain. #FreeDoctorsrss … Read entire article »

(MedPage Today) -- Patients who've had celiac disease ruled out may have another form of gluten sensitivity, but there's little clinical evidence to explain the latter condition, researchers said. (Source: MedPage Today Gastroenterology) … Read entire article »

Are patients with celiac disease at an increased risk for contracting urinary stone disease? Alimentary Pharmacology & Therapeutics (Source: Medscape Today Headlines)jobs … Read entire article »

Conclusions CD-related histological changes are underdiagnosed in community-based hospitals and commercial pathology laboratories. Because incorrect biopsy interpretation can cause underdiagnosis of CD, greater CD awareness and uniformity in small bowel biopsy reporting is required among pathologists. (Source: Journal of Clinical Pathology)news … Read entire article »

Abstract: Background: Celiac disease is more common in patients with hypothyroidism. Malabsorption of levothyroxine has not been studied in this population. We sought to determine if levothyroxine dosing was influenced by the presence and treatment of celiac disease. Methods: This retrospective study was conducted at an academic medical center. Cases had hypothyroidism and celiac disease. Controls had hypothyroidism alone and were selected randomly through the endocrinology clinic records. Celiac disease was defined as representative pathology with positive serology. Age, sex, height, weight, body mass index, creatinine, and medical comorbidity were assessed for cases and controls. The levothyroxine dose and weight-based levothyroxine dose necessary to maintain a euthyroid state was ev... … Read entire article »

Celiac disease (CD) is a disease of the small intestine caused by an immune response to ingested gluten. Idiopathic thrombocytopenic purpura (ITP) is a common acquired bleeding disorder of childhood. It may follow a viral infection or immunization and is caused by an inappropriate response of the immune system. Autoimmune thyroiditis (AT) is a disease that occurs due to autoimmune mechanisms. Celiac disease associated with autoimmune thyroid disease is well known, but the association of CD, autoimmune thyroid disease, and ITP has been reported very rarely in the literature. In the current report, we have presented a case with CD, AT, and acute ITP, because this association is rarely seen, and to emphasize that CD and AT should be kept in mind in patients with ITP. (Source: Clinical and App...MedWorm … Read entire article »

Authors: Carbonell-Barrachina AA, Wu X, Ramírez-Gandolfo A, Norton GJ, Burló F, Deacon C, Meharg AA Abstract Spanish gluten-free rice, cereals with gluten, and pureed baby foods were analysed for total (t-As) and inorganic As (i-As) using ICP-MS and HPLC-ICP-MS, respectively. Besides, pure infant rice from China, USA, UK and Spain were also analysed. The i-As contents were significantly higher in gluten-free rice than in cereals mixtures with gluten, placing infants with celiac disease at high risk. All rice-based products displayed a high i-As content, with values being above 60% of the t-As content and the remainder being dimethylarsinic acid (DMA). Approximately 77% of the pure infant rice samples showed contents below 150 μg kg(-1) (Chinese limit). When daily intake of i-A... … Read entire article »

SummaryT cell recognition of gliadin from dietary gluten is essential for the pathogenesis of celiac disease (CD). The aim of the present study was to analyze whether gliadin‐specific T cells are detectable in the circulation of children with newly diagnosed celiac disease by using a sensitive carboxfluorescein diacetate succinimidyl ester (CFSE) dilution method. Peripheral blood CD4+ T cell responses were analyzed in 20 children at diagnosis of CD and compared to those in 64 healthy control children carrying the CD‐associated HLA‐DQ2 or ‐DQ8 alleles. Deamidated gliadin (gTG)‐specific T cells were detectable in the peripheral blood of over half of the children with CD (11 of 20, 55 %) compared to 15 of 64 (23.4 %) of the control children (p = 0.008). Proliferative responses to gT...tools … Read entire article »

ConclusionGluten‐free diet is still the only practical treatment for patients with coeliac disease. Novel strategies provide promise of alternative adjunctive approaches to diet restriction alone for patients with this disorder. (Source: Alimentary Pharmacology and Therapeutics)MedWorm Sponsor Message: Please have a look at this new site driven by MedWorm: The Breast Cancer Dailyrss … Read entire article »

Authors: Christina Papista, Vassilis Gerakopoulos, Andreas Kourelis, Maria Sounidaki, Anastasia Kontana, Laureline Berthelot, Ivan C Moura, Renato C Monteiro & Minas Yiangou (Source: Laboratory Investigation AOP)MedWorm Sponsor Message: Please support the Doctors In Chains campaign for the medics tortured and sentenced for up to 15 years in Bahrain. #FreeDoctors … Read entire article »