[The new TNM classification of tumors of the esophagogastric junction : Surgical consequences.] Chirurg. 2011 Nov 18; Authors: Schuhmacher C, Novotny A, Feith M, Friess H Abstract The new International Union Against Cancer (UICC) classification in its seventh version has been out since January 2010. It included some important changes for the classification of esophageal and gastric carcinomas compared to the sixth version.For esophageal carcinomas this means a more detailed subdivision of the T and N stages which should, together with the newly introduced prognostic grouping (separate for squamous cell carcinoma and adenocarcinoma) enable a more precise and individualized prediction of prognosis. Another innovation is that positive lymph nodes in the esophageal drainage are...MedWorm Sponsor Message: Find the … Read entire article »

Authors: Wang N, Shen N, Vyse TJ, Anand V, Gunnarson I, Sturfelt G, Rantapää-Dahlqvist S, Elvin K, Truedsson L, Andersson BA, Dahle C, Ortqvist E, Gregersen PK, Behrens TW, Hammarström L Abstract Selective IgA deficiency (IgAD) is the most common primary immunodeficiency in Caucasians. It has previously been suggested to be associated with a variety of concomitant autoimmune diseases. In this review, we present data on the prevalence of IgAD in patients with Graves' disease (GD), systemic lupus erythematosus (SLE), type 1 diabetes (T1D), celiac disease (CD), myasthenia gravis (MG) and rheumatoid arthritis (RA) based both on our own, recent, large scale screening results and literature data. Genetic factors are important for the development of both IgAD and various autoimmune dis...MedWorm Sponsor Message: Please … Read entire article »

We report one case of jejunal free perforation as the initial manifestation of small bowel lymphoma in a 46 year-old man with unsuspected celiac disease. Perforation was the revealing feature of the lymphoma and led to recognition of latent, long standing celiac disease. Multidetector row computed tomography (MDCT) showed pneumoperitoneum, fluid effusion and findings suggestive for celiac disease including diffuse small bowel thickening, paucity of jejunal folds, enlarged mesenteric lymph nodes and focal jejunal mass. Histopathological analysis confirmed perforation of jejunal pleomorphic large cell, enteropathy-associated T-cell lymphoma (EATL) with marked changes of jejunal mucosa consistent with long standing celiac disease. Immunohistochemical staining on jejunal lesion was positive fo...home … Read entire article »

We report one case of jejunal free perforation as the initial manifestation of small bowel lymphoma in a 46 year-old man with unsuspected celiac disease. Perforation was the revealing feature of the lymphoma and led to recognition of latent, long standing celiac disease. Multidetector row computed tomography (MDCT) showed pneumoperitoneum, fluid effusion and findings suggestive for celiac disease including diffuse small bowel thickening, paucity of jejunal folds, enlarged mesenteric lymph nodes and focal jejunal mass. Histopathological analysis confirmed perforation of jejunal pleomorphic large cell, enteropathy-associated T-cell lymphoma (EATL) with marked changes of jejunal mucosa consistent with long standing celiac disease. Immunohistochemical staining on jejunal lesion was positive fo... … Read entire article »

We report one case of jejunal free perforation as the initial manifestation of small bowel lymphoma in a 46 year-old man with unsuspected celiac disease. Perforation was the revealing feature of the lymphoma and led to recognition of latent, long standing celiac disease. Multidetector row computed tomography (MDCT) showed pneumoperitoneum, fluid effusion and findings suggestive for celiac disease including diffuse small bowel thickening, paucity of jejunal folds, enlarged mesenteric lymph nodes and focal jejunal mass. Histopathological analysis confirmed perforation of jejunal pleomorphic large cell, enteropathy-associated T-cell lymphoma (EATL) with marked changes of jejunal mucosa consistent with long standing celiac disease. Immunohistochemical staining on jejunal lesion was positive fo...tools … Read entire article »

We report one case of jejunal free perforation as the initial manifestation of small bowel lymphoma in a 46 year-old man with unsuspected celiac disease. Perforation was the revealing feature of the lymphoma and led to recognition of latent, long standing celiac disease. Multidetector row computed tomography (MDCT) showed pneumoperitoneum, fluid effusion and findings suggestive for celiac disease including diffuse small bowel thickening, paucity of jejunal folds, enlarged mesenteric lymph nodes and focal jejunal mass. Histopathological analysis confirmed perforation of jejunal pleomorphic large cell, enteropathy-associated T-cell lymphoma (EATL) with marked changes of jejunal mucosa consistent with long standing celiac disease. Immunohistochemical staining on jejunal lesion was positive fo...site-map … Read entire article »

We report one case of jejunal free perforation as the initial manifestation of small bowel lymphoma in a 46 year-old man with unsuspected celiac disease. Perforation was the revealing feature of the lymphoma and led to recognition of latent, long standing celiac disease. Multidetector row computed tomography (MDCT) showed pneumoperitoneum, fluid effusion and findings suggestive for celiac disease including diffuse small bowel thickening, paucity of jejunal folds, enlarged mesenteric lymph nodes and focal jejunal mass. Histopathological analysis confirmed perforation of jejunal pleomorphic large cell, enteropathy-associated T-cell lymphoma (EATL) with marked changes of jejunal mucosa consistent with long standing celiac disease. Immunohistochemical staining on jejunal lesion was positive fo... … Read entire article »

We report one case of jejunal free perforation as the initial manifestation of small bowel lymphoma in a 46 year-old man with unsuspected celiac disease. Perforation was the revealing feature of the lymphoma and led to recognition of latent, long standing celiac disease. Multidetector row computed tomography (MDCT) showed pneumoperitoneum, fluid effusion and findings suggestive for celiac disease including diffuse small bowel thickening, paucity of jejunal folds, enlarged mesenteric lymph nodes and focal jejunal mass. Histopathological analysis confirmed perforation of jejunal pleomorphic large cell, enteropathy-associated T-cell lymphoma (EATL) with marked changes of jejunal mucosa consistent with long standing celiac disease. Immunohistochemical staining on jejunal lesion was positive fo... … Read entire article »

We report one case of jejunal free perforation as the initial manifestation of small bowel lymphoma in a 46 year-old man with unsuspected celiac disease. Perforation was the revealing feature of the lymphoma and led to recognition of latent, long standing celiac disease. Multidetector row computed tomography (MDCT) showed pneumoperitoneum, fluid effusion and findings suggestive for celiac disease including diffuse small bowel thickening, paucity of jejunal folds, enlarged mesenteric lymph nodes and focal jejunal mass. Histopathological analysis confirmed perforation of jejunal pleomorphic large cell, enteropathy-associated T-cell lymphoma (EATL) with marked changes of jejunal mucosa consistent with long standing celiac disease. Immunohistochemical staining on jejunal lesion was positive fo...handbook … Read entire article »